I was privileged to work with a number of excellent clinicians at Keele University and one such was Professor Clive Hawkins, a leading authority on multiple sclerosis (MS). A chance meeting led to an idea that we may be able to detect markers of oxidative stress in urine in individuals with MS. We had recently developed a highly successful method of measuring malondialdehyde (MDA) in the urine of babies. A small clinical trial followed in which we measured several markers of oxidative stress in the urine of individuals with relapsing remitting (RRMS) and secondary progressive (SPMS) multiple sclerosis and compared the data with age and gender matched controls. What we found was extraordinary. While we were unable to detect appreciable amounts of specific oxidative markers such as MDA we made the unexpected observation that individuals with MS excreted very high amounts of both iron and aluminium in their urine.
This was the first research to link MS with human exposure to aluminium. However, scrutiny of animal models of aluminium intoxication revealed myelin to be a target of aluminium toxicity. Neurodegeneration of the myelin sheath surrounding the spinal cord is heavily implicated in the aetiology of MS. Could this be the link with increased excretion of aluminium in urine? Are individuals suffering MS also suffering a form of intoxication by aluminium?
It would be another decade before we were finally able to obtain funding to confirm the link between aluminium and multiple sclerosis. Multiple, pun intended, applications to funding bodies including the Multiple Sclerosis Society were unsuccessful. We were finally able to secure funding through an academia/industry partnership involving Spritzer (Malaysian mineral water company) to carry out a clinical trial under the guise of a mineral water study. We had previously shown that silicon-rich mineral water facilitated the excretion of aluminium in individuals with Alzheimer's disease and we hypothesised that the same might be true in MS. The working hypothesis was proven, not only did individuals with MS normally excrete abnormally high amounts of aluminium in their urine but the amount was significantly increased by regular drinking of a silicon-rich mineral water.
The next piece of the aluminium and MS jigsaw came through our research on aluminium in human brain tissue funded primarily by Claire Dwoskin through CMSRI. The study demonstrated unequivocally that individuals who had died with a diagnosis of MS had extraordinarily high amounts of aluminium in their brain tissue. Aluminium-specific fluorescence showed that aluminium was found throughout brain tissue both intracellular, associated with glia, and extracellular as indicated in the figure below.
The image identifies punctate deposits of aluminium (bright orange fluorescence) in the perivascular region of a small blood vessel in white matter taken from the frontal lobe of an individual who died with a diagnosis of MS.
It seems inconceivable that such high amounts of aluminium in brain tissue are not directly associated with the aetiology of MS. However, when this paper was published and received some online attention, the Multiple Sclerosis Society actively campaigned against its findings, tweeting that it should be ignored. Yet another example of how major health charities have been wholly ‘captured’ by the pharmaceutical industry. Think about this next time you decide to do a run or host an event on behalf of these so-called charities. It is perhaps not surprising that the MS Society Twitter account was silent following publication of our study comparing aluminium in brain tissue in MS with control brain tissues.
I have said previously that of all the neurodegenerative diseases linked with human exposure to aluminium, MS ticks all the boxes. I will write about mechanisms of toxicity in future posts but in the meantime aluminium and multiple sclerosis needs to be considered a likely if unwanted marriage.
Namaste, Professor. I am humbled and have great joy in my heart, that I can always look to your intellectually invigorating articles and studies with great hope for the future of mankind. You mentioned the most likely deprecating intentions of big Pharma, but how big an influence does big aluminum have as well? As you probably know, big Pharma did the same thing in the 80s when funding was readily available to HIV/AIDS charities to support the notion that AZT was one of the only hopes for a cure when IN point of fact, as the data now shows, AZT was hastening their demise instead. Or another way to put it: killing them.
Thank you Dr Exley for this excellent post,,another nail in the vaccine coffin 🤔 As you so aptly show , most if not all of the Large Charities are Pharma Captured.10 years it is shocking🤬🤯
Well done for your circuitous route, you are streets ahead, 😁 so sad that you had to find a way, instead of being encouraged lauded for your research.
I sincerely believe due to the Covid Plandemic so many Doctors are waking up, the trickle will become a flood.The message is getting out,even with the MSM Censorship...
I am a natural optimist and most of my awake friends aren’t 🤞🏻I am right.