Science and Aluminium Adjuvants
Arm yourself with some science when you next discuss aluminium adjuvants in vaccines
I must admit that I am often frustrated by uninformed comments concerning aluminium adjuvants in vaccines. My research group began our focus on aluminium adjuvants in about 2009. Largely to redress the widespread ignorance on how they work but also because I recognised my own failings in not addressing this important route of human exposure to aluminium.
Our first significant breakthrough in understanding demonstrated for the first time that aluminium adjuvant was internalised by immune cells. The type of cells found at a vaccine injection site. Specifically, aluminium adjuvant was found in the cytoplasm of these cells in vesicle-like structures of approximately 0.5–1 μm in diameter. The latter size indication is a critical point as I will explain later herein.
We were then able to show that all aluminium adjuvants were not created equal and, as with aluminium toxicity in general, should not be treated as such by those using them and importantly describing their effects. It also became clear in this research that aluminium loaded into immune cells was not immediately cytotoxic and as such lymphocytes, macrophages et c. might act as Trojan horses distributing their toxic cargo throughout the body.
Our observation that aluminium adjuvants were consistently packaged in intracellular vesicles approximately 1 μm in diameter asked an obvious question. What was the size of particles of aluminium adjuvant at the injection site of a vaccine. We used state-of-the-art particle-sizing technology to address this question. No, no, no, to coin a phrase used by the late British Prime Minister Margaret Thatcher, aluminium adjuvants are NOT nanoparticles in physiological media. Please, please, please, stop the nonsense that the toxicity of aluminium adjuvants is in some way associated with them being nanoparticles. The primary particles of the two most common aluminium adjuvants may be described as nanoparticles as they are less than 100nm in size. However, once in any form of solution and especially physiological media these nanoparticles self-aggregate and generally form particles of approximately 3-5 μm in diameter. So, 3000-5000 nm in diameter. Just perhaps what is so intriguing about this is that phagocytic immune cells (cells capable of internalising aluminium adjuvant particles) actually ‘bite off’ micron sized morsels of aluminium adjuvant. These immune cells upon arriving at the vaccine injection site encounter huge aggregates of aluminium adjuvant and their method of dealing with this foreign body is to munch away at it a micron at a time. Fascinating, I am sure that someone could make an excellent cartoon of this important and critical event in the biochemistry of the immune response.
If you would like to find most of the primary research cited above in a single publication then please access our comprehensive review of this subject. If reading science is difficult then view my presentation, still anomalously available on You Tube.
We worked very hard over many years to bring to light the very best science on aluminium adjuvants used in vaccinations and immunotherapy. If you find yourself needing to address this subject then arm yourself with the science and not the non-science (nonsense) that seems to be so regularly repeated.
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How much do the practitioners administering aluminium-adjuvanted vaccines know about these products?
Are they qualified to administer these medical interventions?
I wonder how they obtain voluntary informed consent?
If you think of it as a garbage collection system instead of a war like immune system, it makes sense!
Their job is to pull out the dead trash and get rid of it.
But if they used something that's hard to eliminate in the shots, like aluminum, you create bodies with trash circulating.